Abstract:According to a survey of evolutionary process, constitutes, efficiency and weak links of earthquake disaster prevention system at home and aboard, that its actual situation, main problems and developing trend of the system in China are analyzed. The constitutional framework and science connatation of earthquake disaster prevention system are presented from the following three aspects: prevention technique for potential sourse zone making earthquake damage, organizational management, and ensure measures and its guilding ideology, developing thoughts, overall object and staged object were presented as well. In addition,in the national Twelfth FiveYear Plan, the development directions, primary indicators, prior subjects, science research plans, construction projects, special research projects of the following item: a seismic design reguiroment and technical standards, earthquake disaster preparedness of cities, village, all engineering structures and secondary disasters, early warning on earthquake and emergency handle, public capabilities facing earthquake disaster, resuce and rehabilitate, and ensure abilities on technological innovation, law and policy, organizational management, propagandism and education are put forward. Moreover, the status, part and effect of the China Earthquake Administration in earthquake disaster prevention system, are discussed. The suggests were given for development program of the earthquake disaster prevention system during the National Twelfth FiveYear Plan.